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High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq

We previously used RNA-seq to identify chemicals whose effects on neuronal gene expression mimicked transcriptional signatures of autism, aging, and neurodegeneration. However, this approach was costly and time consuming, which limited our study to testing a single chemical concentration on mixed se...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Simon, Jeremy M., Paranjape, Smita R., Wolter, Justin M., Salazar, Gabriela, Zylka, Mark J.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418307/
https://ncbi.nlm.nih.gov/pubmed/30872602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39016-5
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