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High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq

We previously used RNA-seq to identify chemicals whose effects on neuronal gene expression mimicked transcriptional signatures of autism, aging, and neurodegeneration. However, this approach was costly and time consuming, which limited our study to testing a single chemical concentration on mixed se...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Simon, Jeremy M., Paranjape, Smita R., Wolter, Justin M., Salazar, Gabriela, Zylka, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418307/
https://ncbi.nlm.nih.gov/pubmed/30872602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39016-5
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