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High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq

We previously used RNA-seq to identify chemicals whose effects on neuronal gene expression mimicked transcriptional signatures of autism, aging, and neurodegeneration. However, this approach was costly and time consuming, which limited our study to testing a single chemical concentration on mixed se...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Simon, Jeremy M., Paranjape, Smita R., Wolter, Justin M., Salazar, Gabriela, Zylka, Mark J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418307/
https://ncbi.nlm.nih.gov/pubmed/30872602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39016-5
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