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Revealing the Pharmacophore of Ipomoeassin F through Molecular Editing
Ipomoeassin F, the flagship congener of a resin glycoside family exhibited single-digit nanomolar IC(50) values against several cancer cell lines. To facilitate drug discovery based on this unique yet underexplored natural product, we performed the most sophisticated SAR studies of ipomoeassin F to...
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| Publicado no: | Org Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821163/ https://ncbi.nlm.nih.gov/pubmed/26998757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b00555 |
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