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SR2067 Reveals a Unique Kinetic and Structural Signature for PPARγ Partial Agonism
Synthetic full agonists of PPARγ have been prescribed for the treatment of diabetes due to their ability to regulate glucose homeostasis and insulin sensitization. While the use of full agonists of PPARγ has been hampered due to severe side effects, partial agonists have shown promise due to their d...
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| Publicado no: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819005/ https://ncbi.nlm.nih.gov/pubmed/26579553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00580 |
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