Φορτώνει......
Ligand and receptor dynamics contribute to the mechanism of graded PPARγ agonism
Ligand binding to proteins is not a static process, but rather involves a number of complex dynamic transitions. A flexible ligand can change conformation upon binding its target. The conformation and dynamics of a protein can change to facilitate ligand binding. The conformation of the ligand, howe...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278220/ https://ncbi.nlm.nih.gov/pubmed/22244763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.10.018 |
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