The BH3 mimetic drug ABT-737 induces apoptosis and acts synergistically with chemotherapeutic drugs in thyroid carcinoma cells

BACKGROUND: Patients with dedifferentiated and anaplastic thyroid carcinomas that do not take up radioiodine are resistant to chemotherapeutic treatment and external irradiation and thus are difficult to treat. Direct induction of apoptosis is a promising approach in these apoptosis-resistant tumor...

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Bibliographic Details
Published in:Cancer Cell Int
Main Authors: Broecker-Preuss, Martina, Becher-Boveleth, Nina, Müller, Stefan, Mann, Klaus
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818940/
https://ncbi.nlm.nih.gov/pubmed/27042160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0303-8
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