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Enhanced Methylation Analysis by Recovery of Unsequenceable Fragments
Bisulfite sequencing is a valuable tool for mapping the position of 5-methylcytosine in the genome at single base resolution. However, the associated chemical treatment causes strand scission, which depletes the number of sequenceable DNA fragments in a library and thus necessitates PCR amplificatio...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816320/ https://ncbi.nlm.nih.gov/pubmed/27031619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152322 |
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