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5-Formylcytosine alters the structure of the DNA double helix
The modified base 5-formylcytosine (5fC) was recently identified in mammalian DNA and might be considered as the “seventh” base of the genome. This nucleotide has been implicated in active demethylation mediated by the base excision repair enzyme thymine DNA glycosylase (TDG). Genomics and proteomic...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Struct Mol Biol |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287393/ https://ncbi.nlm.nih.gov/pubmed/25504322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2936 |
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