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5-Formylcytosine alters the structure of the DNA double helix
The modified base 5-formylcytosine (5fC) was recently identified in mammalian DNA and might be considered as the “seventh” base of the genome. This nucleotide has been implicated in active demethylation mediated by the base excision repair enzyme thymine DNA glycosylase (TDG). Genomics and proteomic...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287393/ https://ncbi.nlm.nih.gov/pubmed/25504322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2936 |
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