Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase

BACKGROUND: Methylation of cytosine in DNA (5mC) is an important epigenetic mark that is involved in the regulation of genome function. During early embryonic development in mammals, the methylation landscape is dynamically reprogrammed in part through active demethylation. Recent advances have iden...

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Main Authors: Raiber, Eun-Ang, Beraldi, Dario, Ficz, Gabriella, Burgess, Heather E, Branco, Miguel R, Murat, Pierre, Oxley, David, Booth, Michael J, Reik, Wolf, Balasubramanian, Shankar
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491369/
https://ncbi.nlm.nih.gov/pubmed/22902005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-8-r69
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