A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation

BACKGROUND: DNA methylation (5mC) plays important roles in epigenetic regulation of genome function. Recently, TET hydroxylases have been found to oxidise 5mC to hydroxymethylcytosine (5hmC), formylcytosine (5fC) and carboxylcytosine (5caC) in DNA. These derivatives have a role in demethylation of D...

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Detalhes bibliográficos
Main Authors: Iurlaro, Mario, Ficz, Gabriella, Oxley, David, Raiber, Eun-Ang, Bachman, Martin, Booth, Michael J, Andrews, Simon, Balasubramanian, Shankar, Reik, Wolf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014808/
https://ncbi.nlm.nih.gov/pubmed/24156278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-10-r119
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