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Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania
BACKGROUND: 5-Hydroxymethyluracil (5hmU) is a thymine base modification found in the genomes of a diverse range of organisms. To explore the functional importance of 5hmU, we develop a method for the genome-wide mapping of 5hmU-modified loci based on a chemical tagging strategy for the hydroxymethyl...
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| Vydáno v: | Genome Biol |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5282726/ https://ncbi.nlm.nih.gov/pubmed/28137275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1150-1 |
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