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Selective Chemical Labeling of Natural T Modifications in DNA
[Image: see text] We present a chemical method to selectively tag and enrich thymine modifications, 5-formyluracil (5-fU) and 5-hydroxymethyluracil (5-hmU), found naturally in DNA. Inherent reactivity differences have enabled us to tag 5-fU chemoselectively over its C modification counterpart, 5-for...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2015
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521287/ https://ncbi.nlm.nih.gov/pubmed/25946119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03730 |
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