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Single genome retrieval of context-dependent variability in mutation rates for human germline

BACKGROUND: Accurate knowledge of the core components of substitution rates is of vital importance to understand genome evolution and dynamics. By performing a single-genome and direct analysis of 39,894 retrotransposon remnants, we reveal sequence context-dependent germline nucleotide substitution...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Sahakyan, Aleksandr B., Balasubramanian, Shankar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237266/
https://ncbi.nlm.nih.gov/pubmed/28086752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3440-5
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