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Properties and rates of germline mutations in humans

All genetic variation arises via new mutations, and therefore determining the rate and biases for different classes of mutation is essential for understanding the genetics of human disease and evolution. Decades of mutation rate analyses have focused on a relatively small number of loci because of t...

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Detalhes bibliográficos
Main Authors: Campbell, Catarina D., Eichler, Evan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785239/
https://ncbi.nlm.nih.gov/pubmed/23684843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2013.04.005
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