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Germline de novo mutation rates on exons versus introns in humans
A main assumption of molecular population genetics is that genomic mutation rate does not depend on sequence function. Challenging this assumption, a recent study has found a reduction in the mutation rate in exons compared to introns in somatic cells, ascribed to an enhanced exonic mismatch repair...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7334200/ https://ncbi.nlm.nih.gov/pubmed/32620809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17162-z |
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