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Timing, rates and spectra of human germline mutation
Germline mutations are a driving force behind genome evolution and genetic disease. We investigated genome-wide mutation rates and spectra in multi-sibling families. Mutation rate increased with paternal age in all families, but the number of additional mutations per year differed more than two-fold...
में बचाया:
| में प्रकाशित: | Nat Genet |
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| मुख्य लेखकों: | , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731925/ https://ncbi.nlm.nih.gov/pubmed/26656846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3469 |
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