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The genome-wide effects of ionizing radiation on mutation induction in the mammalian germline

The ability to predict the genetic consequences of human exposure to ionizing radiation has been a long-standing goal of human genetics in the past 50 years. Here we present the results of an unbiased, comprehensive genome-wide survey of the range of germline mutations induced in laboratory mice aft...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Adewoye, Adeolu B., Lindsay, Sarah J., Dubrova, Yuri E., Hurles, Matthew E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389250/
https://ncbi.nlm.nih.gov/pubmed/25809527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7684
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