Nalaganje...
Chemical biology of genomic DNA: minimizing PCR bias†
The exquisite selectivity of chemical reactions enables the study of rare DNA bases. However, chemical modification of the genome can affect downstream analysis. We report a PCR bias caused by such modification, and exemplify a solution with the synthesis and characterization of a cleavable aldehyde...
Shranjeno v:
| izdano v: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5759930/ https://ncbi.nlm.nih.gov/pubmed/25178041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc05107f |
| Oznake: |
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