Rapid Increases in proBDNF after Pilocarpine-Induced Status Epilepticus in Mice Are Associated with Reduced proBDNF Cleavage Machinery123

Brain-derived neurotrophic factor (BDNF) levels are elevated after status epilepticus (SE), leading to activation of multiple signaling pathways, including the janus kinase/signal transducer and activator of transcription pathway that mediates a decrease in GABA(A) receptor α1 subunits in the hippoc...

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Udgivet i:eNeuro
Main Authors: Thomas, Ajay X., Cruz Del Angel, Yasmin, Gonzalez, Marco I., Carrel, Andrew J., Carlsen, Jessica, Lam, Philip M., Hempstead, Barbara L., Russek, Shelley. J., Brooks-Kayal, Amy R.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
Fag:
New Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814566/
https://ncbi.nlm.nih.gov/pubmed/27057559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0020-15.2016
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