Proteolytic cleavage of proBDNF into mature BDNF in the basolateral amygdala is necessary for defeat-induced social avoidance

Brain-derived neurotrophic factor (BDNF) is essential for memory processes. The present study tested whether proteolytic cleavage of proBDNF into mature BDNF (mBDNF) within the basolateral amygdala (BLA) regulates the consolidation of defeat-related memories. We found that acute social defeat increa...

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Detalhes bibliográficos
Publicado no:Learn Mem
Main Authors: Dulka, Brooke N., Ford, Ellen C., Lee, Melissa A., Donnell, Nathaniel J., Goode, Travis D., Prosser, Rebecca, Cooper, Matthew A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793198/
https://ncbi.nlm.nih.gov/pubmed/26980783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.040253.115
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