Proteolytic cleavage of proBDNF into mature BDNF in the basolateral amygdala is necessary for defeat-induced social avoidance

Brain-derived neurotrophic factor (BDNF) is essential for memory processes. The present study tested whether proteolytic cleavage of proBDNF into mature BDNF (mBDNF) within the basolateral amygdala (BLA) regulates the consolidation of defeat-related memories. We found that acute social defeat increa...

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Dettagli Bibliografici
Pubblicato in:Learn Mem
Autori principali: Dulka, Brooke N., Ford, Ellen C., Lee, Melissa A., Donnell, Nathaniel J., Goode, Travis D., Prosser, Rebecca, Cooper, Matthew A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2016
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793198/
https://ncbi.nlm.nih.gov/pubmed/26980783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.040253.115
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