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Discovery and characterization of novel smallmolecule agonists of G protein-coupled receptor 119
AIM: GPR119 is a G protein-coupled receptor (GPCR) that is highly expressed in pancreatic β-cells and intestinal L-cells and facilitates glucose-stimulated insulin secretion (GSIS). GPR119 may represent a novel target for the treatment of metabolic disorders. Here, we sought to identify novel small-...
Enregistré dans:
| Publié dans: | Acta Pharmacol Sin |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813729/ https://ncbi.nlm.nih.gov/pubmed/24681896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.8 |
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