Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman

The sodium (Na(+))-calcium (Ca(2+)) exchanger 1 (NCX1) is an important regulator of intracellular Ca(2+) homeostasis. Serine 68-phosphorylated phospholemman (pSer-68-PLM) inhibits NCX1 activity. In the context of Na(+)/K(+)-ATPase (NKA) regulation, pSer-68-PLM is dephosphorylated by protein phosphat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hafver, Tandekile Lubelwana, Hodne, Kjetil, Wanichawan, Pimthanya, Aronsen, Jan Magnus, Dalhus, Bjørn, Lunde, Per Kristian, Lunde, Marianne, Martinsen, Marita, Enger, Ulla Helene, Fuller, William, Sjaastad, Ivar, Louch, William Edward, Sejersted, Ole Mathias, Carlson, Cathrine Rein
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813481/
https://ncbi.nlm.nih.gov/pubmed/26668322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677898
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