Full-length cardiac Na(+)/Ca(2+) exchanger 1 protein is not phosphorylated by protein kinase A

The cardiac Na(+)/Ca(2+) exchanger 1 (NCX1) is an important regulator of intracellular Ca(2+) homeostasis and cardiac function. Several studies have indicated that NCX1 is phosphorylated by the cAMP-dependent protein kinase A (PKA) in vitro, which increases its activity. However, this finding is con...

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Bibliographische Detailangaben
Hauptverfasser: Wanichawan, Pimthanya, Louch, William E., Hortemo, Kristin H., Austbø, Bjørg, Lunde, Per Kristian, Scott, John D., Sejersted, Ole M., Carlson, Cathrine R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Membrane Transporters, Ion Channels and Pumps
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093950/
https://ncbi.nlm.nih.gov/pubmed/21289289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00196.2010
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