Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman

The sodium (Na(+))-calcium (Ca(2+)) exchanger 1 (NCX1) is an important regulator of intracellular Ca(2+) homeostasis. Serine 68-phosphorylated phospholemman (pSer-68-PLM) inhibits NCX1 activity. In the context of Na(+)/K(+)-ATPase (NKA) regulation, pSer-68-PLM is dephosphorylated by protein phosphat...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Hafver, Tandekile Lubelwana, Hodne, Kjetil, Wanichawan, Pimthanya, Aronsen, Jan Magnus, Dalhus, Bjørn, Lunde, Per Kristian, Lunde, Marianne, Martinsen, Marita, Enger, Ulla Helene, Fuller, William, Sjaastad, Ivar, Louch, William Edward, Sejersted, Ole Mathias, Carlson, Cathrine Rein
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813481/
https://ncbi.nlm.nih.gov/pubmed/26668322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677898
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