Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody

The HIV-1 envelope trimer (Env) is the target of broadly neutralizing antibodies and is being explored as a vaccine candidate to elicit protective antibodies. One of the most promising antigenic and structural mimics of HIV-1 Env is the SOSIP.664-stabilized soluble trimer from the clade A strain BG5...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Cheng, Cheng, Pancera, Marie, Bossert, Adam, Schmidt, Stephen D., Chen, Rita E., Chen, Xuejun, Druz, Aliaksandr, Narpala, Sandeep, Doria-Rose, Nicole A., McDermott, Adrian B., Kwong, Peter D., Mascola, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810637/
https://ncbi.nlm.nih.gov/pubmed/26719262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02380-15
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