Requirement for the E1 Helicase C-Terminal Domain in Papillomavirus DNA Replication In Vivo

The papillomavirus (PV) E1 helicase contains a conserved C-terminal domain (CTD), located next to its ATP-binding site, whose function in vivo is still poorly understood. The CTD is comprised of an alpha helix followed by an acidic region (AR) and a C-terminal extension termed the C-tail. Recent bio...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Bergvall, Monika, Gagnon, David, Titolo, Steve, Lehoux, Michaël, D'Abramo, Claudia M., Melendy, Thomas, Archambault, Jacques
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Genome Replication and Regulation of Viral Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810619/
https://ncbi.nlm.nih.gov/pubmed/26739052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03127-15
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