Inhibition of Human Papillomavirus DNA Replication by an E1-Derived p80/UAF1-Binding Peptide

The papillomavirus E1 helicase is recruited by E2 to the viral origin, where it assembles into a double hexamer that orchestrates replication of the viral genome. We previously identified the cellular WD40 repeat-containing protein p80/UAF1 as a novel interaction partner of E1 from anogenital human...

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Main Authors: Lehoux, Michaël, Fradet-Turcotte, Amélie, Lussier-Price, Mathieu, Omichinski, James G., Archambault, Jacques
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302507/
https://ncbi.nlm.nih.gov/pubmed/22278251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07003-11
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