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Nucleocytoplasmic Shuttling of Bovine Papillomavirus E1 Helicase Downregulates Viral DNA Replication in S Phase

The papillomavirus E1 protein is essential for the initiation of viral replication. We previously showed that the bovine papillomavirus E1 protein is unstable and becomes resistant to ubiquitin-mediated degradation when tightly bound to cyclin E-cyclin-dependent kinase 2 (Cdk2) before the start of D...

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Autors principals: Hsu, Chiung-Yueh, Mechali, Francisca, Bonne-Andrea, Catherine
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797274/
https://ncbi.nlm.nih.gov/pubmed/17035309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01170-06
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