The Structure-Specific Endonuclease Ercc1-Xpf Is Required To Resolve DNA Interstrand Cross-Link-Induced Double-Strand Breaks

Interstrand cross-links (ICLs) are an extremely toxic class of DNA damage incurred during normal metabolism or cancer chemotherapy. ICLs covalently tether both strands of duplex DNA, preventing the strand unwinding that is essential for polymerase access. The mechanism of ICL repair in mammalian cel...

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Detaylı Bibliyografya
Yayımlandı:	Mol Cell Biol
Asıl Yazarlar:	Niedernhofer, Laura J., Odijk, Hanny, Budzowska, Magda, van Drunen, Ellen, Maas, Alex, Theil, Arjan F., de Wit, Jan, Jaspers, N. G. J., Beverloo, H. Berna, Hoeijmakers, Jan H. J., Kanaar, Roland
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis 2004
Konular:	DNA Dynamics and Chromosome Structure
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC480908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15199134/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.13.5776-5787.2004
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The Structure-Specific Endonuclease Ercc1-Xpf Is Required To Resolve DNA Interstrand Cross-Link-Induced Double-Strand Breaks

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