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The active site of the DNA repair endonuclease XPF–ERCC1 forms a highly conserved nuclease motif
XPF–ERCC1 is a structure-specific endonuclease involved in nucleotide excision repair, interstrand crosslink repair and homologous recombination. So far, it has not been shown experimentally which subunit of the heterodimer harbors the nuclease activity and which amino acids contribute to catalysis....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125967/ https://ncbi.nlm.nih.gov/pubmed/11953324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.8.2045 |
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