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The active site of the DNA repair endonuclease XPF–ERCC1 forms a highly conserved nuclease motif

XPF–ERCC1 is a structure-specific endonuclease involved in nucleotide excision repair, interstrand crosslink repair and homologous recombination. So far, it has not been shown experimentally which subunit of the heterodimer harbors the nuclease activity and which amino acids contribute to catalysis....

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Detalhes bibliográficos
Main Authors: Enzlin, Jacqueline H., Schärer, Orlando D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125967/
https://ncbi.nlm.nih.gov/pubmed/11953324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.8.2045
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