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Immunodetection of DNA repair endonuclease ERCC1-XPF in human tissue

The high incidence of resistance to DNA damaging chemotherapeutic drugs and severe side effects of chemotherapy have led to a search for biomarkers able to predict which patients are most likely to respond to therapy. ERCC1-XPF nuclease is required for nucleotide excision repair of helix-distorting...

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Detalhes bibliográficos
Main Authors: Bhagwat, Nikhil R., Roginskaya, Vera Y., Acquafondata, Marie B., Dhir, Rajiv, Wood, Richard D., Niedernhofer, Laura J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739111/
https://ncbi.nlm.nih.gov/pubmed/19723666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1237
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