XPF-ERCC1 Participates in the Fanconi Anemia Pathway of Cross-Link Repair

Interstrand cross-links (ICLs) prevent DNA strand separation and, therefore, transcription and replication, making them extremely cytotoxic. The precise mechanism by which ICLs are removed from mammalian genomes largely remains elusive. Genetic evidence implicates ATR, the Fanconi anemia proteins, p...

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Detalhes bibliográficos
Main Authors: Bhagwat, Nikhil, Olsen, Anna L., Wang, Anderson T., Hanada, Katsuhiro, Stuckert, Patricia, Kanaar, Roland, D'Andrea, Alan, Niedernhofer, Laura J., McHugh, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786876/
https://ncbi.nlm.nih.gov/pubmed/19805513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00086-09
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