XPF-ERCC1 Participates in the Fanconi Anemia Pathway of Cross-Link Repair

Interstrand cross-links (ICLs) prevent DNA strand separation and, therefore, transcription and replication, making them extremely cytotoxic. The precise mechanism by which ICLs are removed from mammalian genomes largely remains elusive. Genetic evidence implicates ATR, the Fanconi anemia proteins, p...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Bhagwat, Nikhil, Olsen, Anna L., Wang, Anderson T., Hanada, Katsuhiro, Stuckert, Patricia, Kanaar, Roland, D'Andrea, Alan, Niedernhofer, Laura J., McHugh, Peter J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786876/
https://ncbi.nlm.nih.gov/pubmed/19805513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00086-09
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk