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XPF-ERCC1 Participates in the Fanconi Anemia Pathway of Cross-Link Repair
Interstrand cross-links (ICLs) prevent DNA strand separation and, therefore, transcription and replication, making them extremely cytotoxic. The precise mechanism by which ICLs are removed from mammalian genomes largely remains elusive. Genetic evidence implicates ATR, the Fanconi anemia proteins, p...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786876/ https://ncbi.nlm.nih.gov/pubmed/19805513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00086-09 |
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