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An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma

Dysregulated metabolism is a hallmark of cancer, manifested through alterations in metabolites. We performed metabolomic profiling on 138 matched clear cell renal cell carcinoma (ccRCC)/normal tissue pairs and found that ccRCC is characterized by broad shifts in central carbon metabolism, one-carbon...

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Détails bibliographiques
Publié dans:Cancer Cell
Auteurs principaux: Hakimi, A Ari, Reznik, Ed, Lee, Chung-Han, Creighton, Chad J, Brannon, A Rose, Luna, Augustin, Aksoy, B. Arman, Liu, Eric Minwei, Shen, Ronglai, Lee, William, Chen, Yang, Stirdivant, Steve M, Russo, Paul, Chen, Ying Bei, Tickoo, Satish K, Reuter, Victor E, Cheng, Emily H., Sander, Chris, Hsieh, James J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809063/
https://ncbi.nlm.nih.gov/pubmed/26766592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.12.004
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