An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma

Dysregulated metabolism is a hallmark of cancer, manifested through alterations in metabolites. We performed metabolomic profiling on 138 matched clear cell renal cell carcinoma (ccRCC)/normal tissue pairs and found that ccRCC is characterized by broad shifts in central carbon metabolism, one-carbon...

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Gepubliceerd in:Cancer Cell
Hoofdauteurs: Hakimi, A Ari, Reznik, Ed, Lee, Chung-Han, Creighton, Chad J, Brannon, A Rose, Luna, Augustin, Aksoy, B. Arman, Liu, Eric Minwei, Shen, Ronglai, Lee, William, Chen, Yang, Stirdivant, Steve M, Russo, Paul, Chen, Ying Bei, Tickoo, Satish K, Reuter, Victor E, Cheng, Emily H., Sander, Chris, Hsieh, James J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809063/
https://ncbi.nlm.nih.gov/pubmed/26766592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.12.004
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