Clinical and Pathologic Impact of Select Chromatin Modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma

BACKGROUND: Historically, VHL was the only frequently mutated gene in clear cell renal cell carcinoma (ccRCC), with conflicting clinical relevance. Excitingly, recent sequencing efforts identified several novel, frequent mutations of histone modifying and chromatin remodeling genes in ccRCC, includi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hakimi, A Ari, Chen, Ying-Bei, Wren, James, Gonen, Mithat, Abdel-Wahab, Omar, Heguy, Adriana, Liu, Han, Takeda, Shugaku, Tickoo, Satish K, Reuter, Victor E, Voss, Martin H, Motzer, Robert J, Coleman, Jonathan A, Cheng, Emily H., Russo, Paul, Hsieh, James J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615105/
https://ncbi.nlm.nih.gov/pubmed/23036577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2012.09.005
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