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Clinical and Pathologic Impact of Select Chromatin Modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma

BACKGROUND: Historically, VHL was the only frequently mutated gene in clear cell renal cell carcinoma (ccRCC), with conflicting clinical relevance. Excitingly, recent sequencing efforts identified several novel, frequent mutations of histone modifying and chromatin remodeling genes in ccRCC, includi...

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書誌詳細
主要な著者: Hakimi, A Ari, Chen, Ying-Bei, Wren, James, Gonen, Mithat, Abdel-Wahab, Omar, Heguy, Adriana, Liu, Han, Takeda, Shugaku, Tickoo, Satish K, Reuter, Victor E, Voss, Martin H, Motzer, Robert J, Coleman, Jonathan A, Cheng, Emily H., Russo, Paul, Hsieh, James J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615105/
https://ncbi.nlm.nih.gov/pubmed/23036577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2012.09.005
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