Clinical and Pathologic Impact of Select Chromatin Modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma

BACKGROUND: Historically, VHL was the only frequently mutated gene in clear cell renal cell carcinoma (ccRCC), with conflicting clinical relevance. Excitingly, recent sequencing efforts identified several novel, frequent mutations of histone modifying and chromatin remodeling genes in ccRCC, includi...

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Bibliografski detalji
Glavni autori: Hakimi, A Ari, Chen, Ying-Bei, Wren, James, Gonen, Mithat, Abdel-Wahab, Omar, Heguy, Adriana, Liu, Han, Takeda, Shugaku, Tickoo, Satish K, Reuter, Victor E, Voss, Martin H, Motzer, Robert J, Coleman, Jonathan A, Cheng, Emily H., Russo, Paul, Hsieh, James J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615105/
https://ncbi.nlm.nih.gov/pubmed/23036577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2012.09.005
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