Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: a Report by MSKCC and the KIRC TCGA Research Network

PURPOSE: To investigate the impact of newly identified chromosome 3p21 epigenetic tumor suppressors PBRM1, SETD2, and BAP1 on cancer specific survival (CSS) of 609 clear cell renal cell carcinoma (ccRCC) patients from two distinct cohorts. PATIENTS AND METHODS: Select sequencing on 3p tumor suppress...

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Huvudupphovsmän: Hakimi, A Ari, Ostrovnaya, Irina, Reva, Boris, Schultz, Nikolaus, Chen, Ying-Bei, Gonen, Mithat, Liu, Han, Takeda, Shugaku, Voss, Martin H, Tickoo, Satish K, Reuter, Victor E, Russo, Paul, Cheng, Emily H., Sander, Chris, Motzer, Robert J., Hsieh, James J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708609/
https://ncbi.nlm.nih.gov/pubmed/23620406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3886
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