Clinical and Pathologic Impact of Select Chromatin Modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma

BACKGROUND: Historically, VHL was the only frequently mutated gene in clear cell renal cell carcinoma (ccRCC), with conflicting clinical relevance. Excitingly, recent sequencing efforts identified several novel, frequent mutations of histone modifying and chromatin remodeling genes in ccRCC, includi...

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Hlavní autoři: Hakimi, A Ari, Chen, Ying-Bei, Wren, James, Gonen, Mithat, Abdel-Wahab, Omar, Heguy, Adriana, Liu, Han, Takeda, Shugaku, Tickoo, Satish K, Reuter, Victor E, Voss, Martin H, Motzer, Robert J, Coleman, Jonathan A, Cheng, Emily H., Russo, Paul, Hsieh, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615105/
https://ncbi.nlm.nih.gov/pubmed/23036577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2012.09.005
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