Mogat1 deletion does not ameliorate hepatic steatosis in lipodystrophic (Agpat2(−/−)) or obese (ob/ob) mice

Reducing triacylglycerol (TAG) in the liver continues to pose a challenge in states of nonalcoholic hepatic steatosis. Monoacylglycerol O-acyltransferase (MOGAT) enzymes convert monoacylglycerol (MAG) to diacylglycerol, a precursor for TAG synthesis, and are involved in a major pathway of TAG synthe...

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Pubblicato in:J Lipid Res
Autori principali: Agarwal, Anil K., Tunison, Katie, Dalal, Jasbir S., Yen, Chi-Liang Eric, Farese, Robert V., Horton, Jay D., Garg, Abhimanyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2016
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808770/
https://ncbi.nlm.nih.gov/pubmed/26880786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M065896
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