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Metabolic, Reproductive, and Neurologic Abnormalities in Agpat1-Null Mice

Defects in the biosynthesis of phospholipids and neutral lipids are associated with cell membrane dysfunction, disrupted energy metabolism, and diseases including lipodystrophy. In these pathways, the 1-acylglycerol-3-phosphate O-acyltransferase (AGPAT) enzymes transfer a fatty acid to the sn-2 carb...

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Опубликовано в: :Endocrinology
Главные авторы: Agarwal, Anil K., Tunison, Katie, Dalal, Jasbir S., Nagamma, Sneha S., Hamra, F. Kent, Sankella, Shireesha, Shao, Xinli, Auchus, Richard J., Garg, Abhimanyu
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695831/
https://ncbi.nlm.nih.gov/pubmed/28973305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00511
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