Lactosylceramide contributes to mitochondrial dysfunction in diabetes

Sphingolipids have been implicated as key mediators of cell-stress responses and effectors of mitochondrial function. To investigate potential mechanisms underlying mitochondrial dysfunction, an important contributor to diabetic cardiomyopathy, we examined alterations of cardiac sphingolipid metabol...

Full description

Saved in:
Bibliographic Details
Published in:J Lipid Res
Main Authors: Novgorodov, Sergei A., Riley, Christopher L., Yu, Jin, Keffler, Jarryd A., Clarke, Christopher J., Van Laer, An O., Baicu, Catalin F., Zile, Michael R., Gudz, Tatyana I.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2016
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808764/
https://ncbi.nlm.nih.gov/pubmed/26900161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M060061
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items