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Lactosylceramide contributes to mitochondrial dysfunction in diabetes

Sphingolipids have been implicated as key mediators of cell-stress responses and effectors of mitochondrial function. To investigate potential mechanisms underlying mitochondrial dysfunction, an important contributor to diabetic cardiomyopathy, we examined alterations of cardiac sphingolipid metabol...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Novgorodov, Sergei A., Riley, Christopher L., Yu, Jin, Keffler, Jarryd A., Clarke, Christopher J., Van Laer, An O., Baicu, Catalin F., Zile, Michael R., Gudz, Tatyana I.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808764/
https://ncbi.nlm.nih.gov/pubmed/26900161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M060061
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