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Long-chain Ceramide Is a Potent Inhibitor of the Mitochondrial Permeability Transition Pore

The sphingolipid ceramide has been implicated in mediating cell death that is accompanied by mitochondrial functional alterations. Moreover, ceramide has been shown to accumulate in mitochondria upon induction of apoptotic processes. In this study, we sought to evaluate the effects of natural, highl...

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Hlavní autoři: Novgorodov, Sergei A., Gudz, Tatyana I., Obeid, Lina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529003/
https://ncbi.nlm.nih.gov/pubmed/18596045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801810200
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