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Long-chain Ceramide Is a Potent Inhibitor of the Mitochondrial Permeability Transition Pore
The sphingolipid ceramide has been implicated in mediating cell death that is accompanied by mitochondrial functional alterations. Moreover, ceramide has been shown to accumulate in mitochondria upon induction of apoptotic processes. In this study, we sought to evaluate the effects of natural, highl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529003/ https://ncbi.nlm.nih.gov/pubmed/18596045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801810200 |
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