N-Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

Persistent opening of the mitochondrial permeability transition pore (PTP), an inner membrane channel, leads to mitochondrial dysfunction and renders the PTP a therapeutic target for a host of life-threatening diseases. Herein, we report our effort toward identifying small-molecule inhibitors agains...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ChemMedChem
Egile Nagusiak: Roy, Sudeshna, Šileikytė, Justina, Neuenswander, Benjamin, Hedrick, Michael P., Chung, Thomas D. Y., Aubé, Jeffrey, Schoenen, Frank J., Forte, Michael A., Bernardi, Paolo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948641/
https://ncbi.nlm.nih.gov/pubmed/26693836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500545
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