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N-Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

Persistent opening of the mitochondrial permeability transition pore (PTP), an inner membrane channel, leads to mitochondrial dysfunction and renders the PTP a therapeutic target for a host of life-threatening diseases. Herein, we report our effort toward identifying small-molecule inhibitors agains...

詳細記述

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書誌詳細
出版年:ChemMedChem
主要な著者: Roy, Sudeshna, Šileikytė, Justina, Neuenswander, Benjamin, Hedrick, Michael P., Chung, Thomas D. Y., Aubé, Jeffrey, Schoenen, Frank J., Forte, Michael A., Bernardi, Paolo
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948641/
https://ncbi.nlm.nih.gov/pubmed/26693836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500545
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