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Tolerance to the anti-nociceptive and hypothermic effects of morphine are mediated by multiple isoforms of c-Jun N-terminal Kinase

The abuse and overdose of opioid drugs are growing public health problems, globally. While progress has been made towards understanding the mechanisms governing tolerance to opioids, the exact cellular machinery involved remains unclear. However, there is growing evidence to suggest that c-Jun N-ter...

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Publicat a:Neuroreport
Autors principals: Yuill, Matthew B, Zee, Michael L, Marcus, David, Morgan, Daniel J
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808337/
https://ncbi.nlm.nih.gov/pubmed/26914092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000551
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