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Measuring the Constitutive Activation of c-Jun N-terminal Kinase Isoforms
The c-Jun N-terminal kinases (JNK) are important regulators of cell growth, proliferation, and apoptosis. JNKs are typically activated by a sequence of events that include phosphorylation of its T-P-Y motif by an upstream kinase, followed by homodimerization and translocation to the nucleus. Constit...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079000/ https://ncbi.nlm.nih.gov/pubmed/21036249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381298-8.00026-5 |
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