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Measuring the Constitutive Activation of c-Jun N-terminal Kinase Isoforms

The c-Jun N-terminal kinases (JNK) are important regulators of cell growth, proliferation, and apoptosis. JNKs are typically activated by a sequence of events that include phosphorylation of its T-P-Y motif by an upstream kinase, followed by homodimerization and translocation to the nucleus. Constit...

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Autors principals: Nitta, Ryan T., Badal, Shawn S., Wong, Albert J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079000/
https://ncbi.nlm.nih.gov/pubmed/21036249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381298-8.00026-5
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