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Activation by phosphorylation and purification of human c-Jun N-terminal Kinase (JNK) isoforms in milligram amounts
c-Jun N-terminal kinases (JNKs) are part of the mitogen activated protein kinase (MAPK) signaling cascade. They are activated through dual phosphorylation of two residues in the activation loop, a threonine and a tyrosine, by MAP2 kinases (MKK4 and 7) in response to various extracellular stresses su...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991412/ https://ncbi.nlm.nih.gov/pubmed/20709173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2010.08.002 |
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