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GSTpi modulates JNK activity through a direct interaction with JNK substrate, ATF2

Human GSTpi, an important detoxification enzyme, has been shown to modulate the activity of JNKs by inhibiting apoptosis and by causing cell proliferation and tumor growth. In this work, we describe a detailed analysis of the interaction in vitro between GSTpi and JNK isoforms (both in their inactiv...

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Detalhes bibliográficos
Main Authors: Thévenin, Anastasia F, Zony, Chati L, Bahnson, Brian J, Colman, Roberta F
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125868/
https://ncbi.nlm.nih.gov/pubmed/21384452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.609
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